The original capsule production has a great article! What is the main role of capsule hardness tester?

Capsule is a common form of medicine, although this small pill, in fact, its production is very important, this process requires the capsule hardness instrument. When particles are used as the filling material of capsules, the indexes to be examined are hygroscopicity, fluidity, bulk density, solubility and stability. The size of the capsule is indeed determined by the bulk density and dose of the filler. Taking the particle as an example, it is generally advisable to determine the bulk density of the particle first, and then calculate the required volume according to the clinical dose to determine the type of the capsule to be selected.

　Generally required particle hardness, is due to the capsule shell requirements of water, water limit is low, wet particles drying time is long, particle hardness is naturally large; Dense, it should be said that the heap density is high, the capsule has volume limitation, the fluffy granule capsule can not be filled to reach the specification.

The release of dissolved capsules after ingestion is not associated with hardness or density. Therefore, it should be the requirement in the production process. In the process of drying wet particles, if the particles are loose, the solvent volatilizes too fast, the drug will be brought to the surface of the particles, which affects the drug release speed of some sustained-release particles. The loose particles are easy to produce fine powder when sieving.

For soft capsule hardness test and development of the capsule hardness tester. Modular design allows for rapid disassembly and assembly, saving time and trouble when servicing or calibration is required. Two pressure options 0-2 N or 0-20 N. Users can easily change according to requirements, according to the shape or quantity of capsules to provide different positioning device disc.